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The most common side effects of Cialis include headaches, back pain, nasal congestion (stuffy nose), upper respiratory infection, and. Background: The PDE5 inhibitors augment the blood pressure (BP)-lowering effects of nitrates, yet the time Gordonii Hoodia Loss Pill Weight course of this interaction is unclear. Do not take Cialis (tadalafil) if you are also using a nitrate drug for chest pain or heart problems. Nitrates are used to treat the chest pain associated with Viagra (sildenafil), Levitra (vardenafil), or Cialis (tadalafil). Do not take Cialis if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as “poppers”. The most common side effects of Cialis include headaches, back pain, nasal congestion (stuffy nose), upper respiratory infection, and. Similarly, nitrates must never be used by men who take CIALIS. 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